The short answer is YES but there are many options
1) On an XY chart of your data use Insert Trendline; specify Linear and
specify Display Equation
2) Use function SLOPE & INTERCEPT to get these statistics from your data
3) Use LINEST for same purpose but with more statistics
4) If you have Analysis ToolPac installed; use Tools | Data Analysis and
select Regression

a) Have a look at these in Help
be) Google with search term: Excel Regression
c) Try a simple Excel book (from library or second hand from
www.abebooks.com)

Then come back with more details of the data and your needs so we can get
specific.
You
best wishes