You need a macro to do the clearing.  Here is the new macro:

Private Sub Worksheet_Change(ByVal Target As Range)
If Intersect(Target, Range("E12:E500")) Is Nothing Then Exit Sub
If Target.Value <> "C" Then Exit Sub
Application.EnableEvents = False
   Target.Offset(0, 9).Copy Target.Offset(0, 10)
   Target.Offset(0, 9).Clear
Application.EnableEvents = True
End Sub

You don't need to be an expert on VBE.
Because it is worksheet code, it is very easy to install and automatic to use:

1. right-click the tab name near the bottom of the Excel window
2. select View Code - this brings up a VBE window
3. paste the stuff in and close the VBE window

If you have any concerns, first try it on a trial worksheet.

If you save the workbook, the macro will be saved with it.

To remove the macro:

1. bring up the VBE windows as above
2. clear the code out
3. close the VBE window

To learn more about macros in general, see:

http://www.mvps.org/dmcritchie/excel/getstarted.htm

To learn more about Event Macros (worksheet code), see:

http://www.mvps.org/dmcritchie/excel/event.htm

Rudy

A formula cannot delete anything, only return values.

The term "Transpose" is not correct in this case.

Transpose in Excel is to change orientation from east-west to north-south or
opposite.

You just want cells in N12:N500 cut and pasted to cells in O12:O50 which is a
"transfer"

Change the code to..................

Private Sub Worksheet_Change(ByVal Target As Range)
On Error GoTo endit
If Intersect(Target, Range("C12:C500")) Is Nothing Then Exit Sub
          Application.EnableEvents = False
             For Each cell In Target
                If Target.Value = "C" And Target.Offset(0, 11) _
                .Value <> "" Then
                With Target
             .Offset(0, 12).Value = Target.Offset(0, 11).Value
          .Offset(0, 11).ClearContents
       End With
     End If
   Next
endit:
Application.EnableEvents = True
End Sub

Right-click on the sheet tab and "View Code".  Copy/paste the code into the
module that opens.

Alt + q to return to Excel.

With data in N12:N500 start entering letters in column C.

Whenever you enter a "C" the data in N will go to O.

Gord Dibben  MS Excel MVP