If you save the workbook that way (Sheetx active and B2 selected), it'll open
that way.

Or you could use a macro that runs when you open the workbook:

sub Auto_Open()
 application.goto worksheets("sheetX").range("b2"), scroll:=true
end sub

And if you're new to macros, you may want to read David's intro:
http://www.mvps.org/dmcritchie/excel/getstarted.htm

Your file will open to the same worksheet and cell that you leave it on, upon
closing it.  So just leave your cursor on Cell B2 on the sheet that you want
-- Hit Save, and your done.

Arla