Yes, with a mail merge to Word.

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Sue Mosher, Outlook MVP
Author of
Microsoft Outlook Programming - Jumpstart for
Administrators, Power Users, and Developers
http://www.outlookcode.com/jumpstart.aspx
> My email server only allows me to have 25 recipients in
> one email at a time. I am able to send 3000 in a day. Is
> it possible to set up a list of 3000 addresses and have
> outlook send off the same email automatically 3000 times
> but with a different recipient per email.