Yes, the Outlook Security Update...

If you use the Exchange Server look on Sue
Mosher's Slipstick site for the
"Administrative Options for the Outlook E-mail
Security Update:"
http://www.slipstick.com/outlook/esecup/admin.htm

or if you wrote the app to fix your code and write future apps:

Dmitry Streblechenko's Outlook Redemption and Spy:
http://www.dimastr.com/redemption/
http://www.dimastr.com/outspy/

and finally:

If your computer is kept up to date with a virus checker,
AND you keep your Internet Explorer patched up. However
this does remove that security for everything:

Express ClickYes 1.0.1
http://www.express-soft.com/mailmate/clickyes.html
Express ClickYes is a tiny program that sits in the System Tray and clicks
the Yes button on behalf of you, when Outlook's Security Guard opens prompt
dialog saying that a program is trying to send an email with Outlook or
access its address book. FREE download.

I have an app that needs to send mail via my outlook
profile.  When the app attempts to do so, I get the
message, ....trying to send mail, select ok to allow
this.  Well I need Outlook to always allow this, is there
a way I can set Outlook to allow this app to send mail
without giving me the option box.