You're not using the .prf file to create a new default profile every time you start Outlook, are you? That will overwrite any previous profile-specific settings, including per-account signatures.

Signature
Sue Mosher, Outlook MVP
Author of Configuring Microsoft Outlook 2003
http://www.turtleflock.com/olconfig/index.htm
and Microsoft Outlook Programming - Jumpstart for
Administrators, Power Users, and Developers
http://www.outlookcode.com/jumpstart.aspx
>I have my outlook.prf file working fine except I notice that if I create a
> signature in Outlook, then log off, then log back in and create a new email
[quoted text clipped - 11 lines]
> OverwriteProfile=No
> ModifyDefaultProfileIfPresent=FALSE
Bigtech Ron - 02 Mar 2006 18:50 GMT
Sue:
I'm not wanting to. I'm trying to get it so that it will only create a
profile if one is needed.
I thought this statement made sure of this:
ModifyDefaultProfileIfPresent=FALSE
> You're not using the .prf file to create a new default profile every time you start Outlook, are you? That will overwrite any previous profile-specific settings, including per-account signatures.
> >I have my outlook.prf file working fine except I notice that if I create a
[quoted text clipped - 12 lines]
> > OverwriteProfile=No
> > ModifyDefaultProfileIfPresent=FALSE
Sue Mosher [MVP-Outlook] - 02 Mar 2006 19:08 GMT
The settings you have in your .prf file will create a new default profile named Outlook unless there is already a profile named Outlook present. So, if every user has a profile named Outlook Settings but not a profile named Outlook, your .prf file will create a new profile named Outlook and make it the default ... and that new profile will have no autosignatures configured.

Signature
Sue Mosher, Outlook MVP
Author of Configuring Microsoft Outlook 2003
http://www.turtleflock.com/olconfig/index.htm
and Microsoft Outlook Programming - Jumpstart for
Administrators, Power Users, and Developers
http://www.outlookcode.com/jumpstart.aspx
> Sue:
>
[quoted text clipped - 22 lines]
>> > OverwriteProfile=No
>> > ModifyDefaultProfileIfPresent=FALSE