Sorry about that, I wanted to keep it brief.  Too brief  I guess.

My email goes into the outbox and basically sits there.  There is no
acknowledgement that anything was sent and as a result, nothing shows up in
the sent folder.  I don't get an error message or even see a time out.  I
was having the same issue with Outlook Express and Thunderbird.  I talked
with Comcast and they suggested that I change the ports to 587 from 25.  I
did that and they worked.

Just to fill in a couple of more pieces.  Comcast is my ISP for access to
the internet and thus I use (smtp.comcast.net).  Incoming mail comes through
another isp, where my domain has been kept for many years.
(mail.vgernet.net).  I am getting mail in.

The furstrating part is that this was not a problem yesterday morning.  It
is also where I run my business.  I use Outlook as my database and
everything runs through it.