Assuming you are using Publisher 2003 refer to:
http://www.publishermvps.com/WebDesign/Version2003/tabid/33/Default.aspx
There are two good articles there about publishing your website. Also refer
to the FAQ page for common errors.
DavidF
> I followed the instructions given to me by my domain which is to save my
> publisher web design to ftp:username.com however, it would not save to my
> domain. Any possible solutions?